- Amy
- Bender
- Dwight
- Fry
- Gypsy
- Hattie
- Hermes
- Inez
- Debut: Ironside
- Debut: Jonnie Peacock
- Kif
- Debut: Joe Swanson
- LaBarbara
- Leela
- Leo
- Linda
- Morbo
- Debut: Oscar Pistorius
- Poopenmeyer
- Debut: Richard Whitehead
- Debut: Road Runner
- Ron Whitey
- Scruffy
- Smitty
- Stephen Hawking
- Debut: Wile E. Coyote
- URL
- Zapp
- Zoidberg